KEGG   Homo sapiens (human): 7443
Entry
7443              CDS       T01001                                 
Symbol
VRK1, HMNR10, PCH1, PCH1A
Name
(RefSeq) VRK serine/threonine kinase 1
  KO
K08816  vaccinia related kinase [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Disease
H00856  Distal hereditary motor neuropathies
H00897  Pontocerebellar hypoplasia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    7443 (VRK1)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     7443 (VRK1)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: CK1 group
  VRK family
   7443 (VRK1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 Pkinase_fungal Kinase-like EcKL Pox_ser-thr_kin RIO1 APH
Other DBs
NCBI-GeneID: 7443
NCBI-ProteinID: NP_003375
OMIM: 602168
HGNC: 12718
Ensembl: ENSG00000100749
UniProt: Q99986
Structure
Position
14:96797382..96881609
AA seq 396 aa
MPRVKAAQAGRQSSAKRHLAEQFAVGEIITDMAKKEWKVGLPIGQGGFGCIYLADMNSSE
SVGSDAPCVVKVEPSDNGPLFTELKFYQRAAKPEQIQKWIRTRKLKYLGVPKYWGSGLHD
KNGKSYRFMIMDRFGSDLQKIYEANAKRFSRKTVLQLSLRILDILEYIHEHEYVHGDIKA
SNLLLNYKNPDQVYLVDYGLAYRYCPEGVHKEYKEDPKRCHDGTIEFTSIDAHNGVAPSR
RGDLEILGYCMIQWLTGHLPWEDNLKDPKYVRDSKIRYRENIASLMDKCFPEKNKPGEIA
KYMETVKLLDYTEKPLYENLRDILLQGLKAIGSKDDGKLDLSVVENGGLKAKTITKKRKK
EIEESKEPGVEDTEWSNTQTEEAIQTRSRTRKRVQK
NT seq 1191 nt   +upstreamnt  +downstreamnt
atgcctcgtgtaaaagcagctcaagctggaagacagagctctgcaaagagacatcttgca
gaacaatttgcagttggagagataataactgacatggcaaaaaaggaatggaaagtagga
ttacccattggccaaggaggctttggctgtatatatcttgctgatatgaattcttcagag
tcagttggcagtgatgcaccttgtgttgtaaaagtggaacccagtgacaatggacctctt
tttactgaattaaagttctaccaacgagctgcaaaaccagagcaaattcagaaatggatt
cgtacccgtaagctgaagtacctgggtgttcctaagtattgggggtctggtctacatgac
aaaaatggaaaaagttacaggtttatgataatggatcgctttgggagtgaccttcagaaa
atatatgaagcaaatgccaaaaggttttctcggaaaactgtcttgcagctaagcttaaga
attctggatattctggaatatattcacgagcatgagtatgtgcatggagatatcaaggcc
tcaaatcttcttctgaactacaagaatcctgaccaggtgtacttggtagattatggcctt
gcttatcggtactgcccagaaggagttcataaagaatacaaagaagaccccaaaagatgt
cacgatggcactattgaattcacgagcatcgatgcacacaatggcgtggccccatcaaga
cgtggtgatttggaaatacttggttattgcatgatccaatggcttactggccatcttcct
tgggaggataatttgaaagatcctaaatatgttagagattccaaaattagatacagagaa
aatattgcaagtttgatggacaaatgttttcctgagaaaaacaaaccaggtgaaattgcc
aaatacatggaaacagtgaaattactagactacactgaaaaacctctttatgaaaattta
cgtgacattcttttgcaaggactaaaagctataggaagtaaggatgatggcaaattggac
ctcagtgttgtggagaatggaggtttgaaagcaaaaacaataacaaagaagcgaaagaaa
gaaattgaagaaagcaaggaacctggtgttgaagatacggaatggtcaaacacacagaca
gaggaggccatacagacccgttcaagaaccagaaagagagtccagaagtaa

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Ontology (3)   
   KEGG BRITE (3)   
Disease (5)   
   KEGG DISEASE (2)   
   OMIM (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   HGNC (1)   
   Ensembl (1)   
   RIKEN BRC-DNA (1)   
   OC (1)   
Protein sequence (18)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (16)   
DNA sequence (32)   
   RefSeq(nuc) (16)   
   GenBank (8)   
   EMBL (8)   
3D Structure (24)   
   PDB (24)   
Protein domain (9)   
   Pfam (9)   
All databases (102)   

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